Multiple Cranial Mononeuropathies With Acetylcholine Receptor Antibody in Mitochondrial Diabetes
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چکیده
منابع مشابه
Mitochondrial ophthalmoplegia with fatigable weakness and elevated acetylcholine receptor antibody.
A 25-year-old man with chronically progressive ptosis and bilateral ophthalmoplegia displayed fatigability and fluctuation of ptosis, an abnormal single-fiber electromyogram, and a markedly elevated acetylcholine receptor antibody level. Yet a muscle biopsy showed clear evidence of a mitochondrial cytopathy, and the clinical features did not improve after treatment with prednisone. This case em...
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When pooled immunoglobulin G (IgG) from patients with multiple sclerosis (MS) was used to probe a human fetal spinal cord λgt 11 cDNA library, the IgG was found to bind to a predicted epitope of human mitochondrial ND4 sequence. To investigate the involvement of the ND4 as an autoantigen in MS, we determined the presence of specific antibody in the serum of MS patients and serum samples of...
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INTRODUCTION We report a rare case of fulminant vasculitic mononeuropathy resulting in brachial diplegia, with suspected brainstem and autonomic nervous system involvement in a patient with diabetes mellitus. CASE PRESENTATION A 58-year-old Hispanic Caucasian man with diabetes mellitus presented with a 1-year history of progressive bilateral upper extremity weakness, orthostatic intolerance a...
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when pooled immunoglobulin g (igg) from patients with multiple sclerosis (ms) was used to probe a human fetal spinal cord λgt 11 cdna library, the igg was found to bind to a predicted epitope of human mitochondrial nd4 sequence. to investigate the involvement of the nd4 as an autoantigen in ms, we determined the presence of specific antibody in the serum of ms patients and serum samples of some...
متن کاملModulation of acetylcholine receptor by antibody against the receptor.
Antibody against acetylcholine receptor induces an increase in the rate of degradation of acetylcholine receptors on a mouse cell line (BC(3)H-1) and cultured rat skeletal muscle. The increased rate of degradation results in a lowered density of acetylcholine receptors on muscle membrane and a lowered sensitivity to iontophoretically applied acetylcholine. The modulation of acetylcholine recept...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2003
ISSN: 0149-5992,1935-5548
DOI: 10.2337/diacare.26.4.1318